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KMID : 0607520190270020181
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Korean Journal of Psychosomatic Medicine
2019 Volume.27 No. 2 p.181 ~ p.190
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Association between Omega Fatty Acid Intake and Suicidality : Sex Differences in the General Korean Population
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Hur Yang-Im
Lee Jung-Hyun
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Abstract
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Objectives：Epidemiological studies in other countries show that a low intake of omega-3 fatty acids (FAs) increases the risk of depression or suicidality. However, no studies have investigated the associations of suicidality with omega-3 FAs in Korea. Hence, this cross-sectional study aimed to investigate the effects of omega FAs on suicidality in the general South Korean population.
Methods：The data in this study were sourced from adults (n=215,860) who completed the Sixth Korea National Health and Nutrition Examination Survey (KNHANES VI), and the associations between omega FAs and suicidality were analyzed using multivariate logistic regressions.
Results：Our results demonstrated that high omega-3 FA intake was associated with a decreased risk of suicide (OR=0.83, 95% CI : 0.71-0.98) and the high omega-6 to omega-3 FA ratio was associated with an increased risk of suicide (OR=1.25, 95% CI : 1.02-1.54). Additionally, a high intake of omega-3 FAs was associated with a decreased risk of suicide in men, but not in women (OR=0.72, 95% CI : 0.59-0.88).
Conclusions：Overall, our findings suggest that a lower intake of omega-3 FA is associated with the increased risk of suicidality in the general Korean population, especially in men.
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KEYWORD
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Suicide, Depression, Polyunsaturated fatty acids, Omega-3-fatty acid, Omega-6-fatty acid
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